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DBCO-S-S-PEG3-biotin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
DBCO-S-S-PEG3-biotin图片
CAS NO:1430408-09-5
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议

产品介绍
DBCO-S-S-PEG3-biotin 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。
Cas No.1430408-09-5
别名生物素-PEG3-二硫-DBCO
分子式C42H56N6O8S3
分子量869.12
溶解度DMSO : 100 mg/mL (115.06 mM; Need ultrasonic)
储存条件Store at -20°C, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DBCO-S-S-PEG3-biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562