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Bis-propargyl-PEG4
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Bis-propargyl-PEG4图片
CAS NO:159428-42-9
包装与价格：
包装价格(元)
50mg电议
100mg电议
250mg电议

产品介绍
Bis-propargyl-PEG4 是一种用于合成 PORTAC 的 PROTAC linker，属于 PEG 类。Bis-propargyl-PEG2 被用于合成去甲万古霉素。
Cas No.159428-42-9
别名丙炔基-四聚乙二醇-丙炔基
分子式C14H22O5
分子量270.32
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers[1][2].

Bis-propargyl-PEG4 can be used in the synthesis of demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis[2].

[1]. Pearlie BURNETTE, et al. Dimeric immuno-modulatory compounds against cereblon-based mechanisms. WO2020014489A2.
[2]. Jiang, et al. Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis. Tetrahedron, 2018: 74(27), 3527-3533.