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Lenalidomide-C5-amido-Boc
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Lenalidomide-C5-amido-Boc图片
CAS NO:2138441-25-3
包装与价格：
包装价格(元)
100mg电议
500mg电议

产品介绍
Lenalidomide-C5-amido-Boc 是一种基于 Lenalidomide 的，可募集 CRBN 蛋白的 Cereblon 配体。Lenalidomide-C5-amido-Boc 可通过 linker 与靶蛋白配体连接，形成 PROTAC 分子。
Cas No.2138441-25-3
分子式C23H31N3O5
分子量429.51
储存条件Store at -20°C, sealed storage, away from moisture and light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Lenalidomide-C5-amido-Boc is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-amido-Boc can be connected to the ligand for protein by a linker to form PROTAC[1].

[1]. Wang, Shaomeng, et al. Preparation of phthalimide-based compounds as monofunctional intermediates for ligand-dependent target protein degradation. World Intellectual Property Organization, WO2017176958 A1 2017-10-12.
[2]. Robbins, Daniel, et al. WBifunctional compounds for degrading BTK via ubiquitin proteasome pathway. World Intellectual Property Organization, WO2021091575 A1 2021-05-14.