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Bromo-PEG2-bromide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bromo-PEG2-bromide图片
CAS NO:31255-10-4
包装与价格:
包装价格(元)
50mg电议
100mg电议

产品介绍
Bromo-PEG2-bromide 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC。
Cas No.31255-10-4
别名溴代-三聚乙二醇-溴代
分子式C6H12Br2O2
分子量275.97
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Bromo-PEG2-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Chen TH, et al. Metal-organic frameworks constructed from crown ether-based 1,4-benzenedicarboxylic acid derivatives. Dalton Trans. 2016 Feb 21;45(7):3063-9.