Tilfrinib 是一种有效的选择性乳腺肿瘤激酶(Brk)抑制剂（IC50 = 3.15 nM），具有抗增殖和抗肿瘤活性。

Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) which displays anti-proliferative and anti-tumor activities.

Tilfrinib is against MCF7, HS-578/T, and BT-549 cells with GI50 values of 0.99, 1.02 and 1.58 μM[2].

1600515-49-8

C17H13N3O

275.3

DMSO:112.5mg/mL (408.6mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years