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Mal-PEG10-NHS ester
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mal-PEG10-NHS ester图片
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议

产品介绍
Mal-PEG10-NHS ester 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
分子式C31H50N2O16
分子量706.73
溶解度DMSO : 100 mg/mL (141.50 mM; Need ultrasonic)
储存条件4°C, away from moisture
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Mal-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-991.