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(6S)-5,6,7,8-tetrahydro-L-Biopterin(sulfate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(6S)-5,6,7,8-tetrahydro-L-Biopterin(sulfate)图片
CAS NO:109784-74-9
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍
A diastereomer of (6R)-5,6,7,8-tetrahydro-L-biopterin
Cas No.109784-74-9
Canonical SMILESO=S(O)(O)=O.O=C1C2=C(NC(N)=N1)NC[C@@](N2)([H])[C@@H](O)[C@@H](O)C
分子式C9H15N5O3• XH2SO4
分子量241.2
溶解度Water: 10 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(6S)-5,6,7,8-tetrahydro-L-Biopterin is a diastereomer of (6R)-5,6,7,8-tetrahydro-L-biopterin , a cofactor for tyrosine, tryptophan, and phenylalanine hydroxylases and nitric oxide synthase (NOS).1,2,3,4

1.Ishii, A., Hagihara, M., Matsuura, S., et al.Effect of (6R)- and (6S)-tetrahydrobiopterin on L-3,4-dihydroxyphenylalanine (DOPA) formation in NRK fibroblasts transfected with human tyrosine hydroxylase type 2 cDNANeurochem. Int.17(4)625-632(1990) 2.Kappock, T.J., and Caradonna, J.P.Pterin-dependent amino acid hydroxylasesChem. Rev.96(7)2659-2756(1996) 3.Mayer, B., and Werner, E.R.In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxideN.-S. Arch. Pharmacol.351(5)453-463(1995) 4.Kraft, V.A.N., Bezjian, C.T., Pfeiffer, S., et al.GTP cyclohydrolase 1/tetrahydrobiopterin counteract ferroptosis through lipid remodelingACS Cent. Sci.6(1)41-53(2020)