| CAS NO: | 1173021-02-7 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| Cas No. | 1173021-02-7 |
| 别名 | 咔唑-D7,(±)-Carazolol-d7; DL-Carazolol-d7; Suacron-d7 |
| Canonical SMILES | OC(CNC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])COC1=C(C(C=CC=C2)=C2N3)C3=CC=C1 |
| 分子式 | C18H15D7N2O2 |
| 分子量 | 305.4 |
| 溶解度 | DMSO: slightly,Methanol: very slightly |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Carazolol-d7 is intended for use as an internal standard for the quantification of carazolol by GC- or LC-MS. Carazolol is a β-adrenergic receptor (β-AR) ligand (Kds = 0.2, 0.03, and 4.47 nM for the human β1-, β2-, and β3-ARs, respectively).1It reduces epinephrine-induced increases in mean arterial blood pressure and heart rate in conscious pigs when administered at a dose of 10 µg/kg.2Carazolol has been found in wastewater effluent.3Formulations containing carazolol have been used to reduce stress in livestock during transport. 1.Baker, J.G.The selectivity of β-adrenoceptor agonists at human β1-, β2- and β3-adrenoceptorsBr. J. Pharmacol.160(5)1048-1061(2010) 2.Gregory, N.G., and Wilkins, L.J.The effect of carazolol on the cardiovascular responses to adrenaline in stress sensitive pigsVet. Res. Commun.5(3)277-283(1982) 3.Ternes, T.A.Occurrence of drugs in German sewage treatment plants and riversWater Res.32(11)3245-3260(1998) |
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