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Fmoc-Val-Ala-PAB-OH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fmoc-Val-Ala-PAB-OH图片
CAS NO:1394238-91-5
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议

产品介绍
Fmoc-Val-Ala-PAB-OH 是一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
Cas No.1394238-91-5
分子式C30H33N3O5
分子量515.6
溶解度DMSO : 33.33 mg/mL (64.64 mM; ultrasonic and warming and heat to 80℃)
储存条件Store at -20°C, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.