HS-10296 hydrochloride 是一种 EGFR 激活突变和 T790M 耐药突变的小分子抑制剂，用于非小细胞肺癌的研究，对 T790M、T790M/L858R 和 T790M/Del19 表现出较强的抑制活性，对野生型的抑制作用较弱。

HS-10296 hydrochloride is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.

HS-10296 hydrochloride is an orally available inhibitor of the epidermal growth factor receptor (EGFR) mutant form T790M, with potential antineoplastic activity, which canbe used to treat NSCLC[1].

2134096-03-8

C30H36ClN7O2

562.12

HS-10296 hydrochloride;盐酸阿美替尼

DMSO:83.33 mg/mL (148.25 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years