AZ10606120 dihydrochloride 是一种特异性和高亲和力的 P2X7 拮抗剂（在人和大鼠中IC50 = 10 nM ）。AZ10606120 dihydrochloride 可减少肿瘤生长并具有抗抑郁作用。 AZ10606120 二盐酸盐对其他 P2XR 亚型几乎没有影响。

AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth[1]. AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of ~10 nM and it is little or no effect at other P2XR subtypes.

607378-18-7

C25H36Cl2N4O2

495.49

H2O:1.5 mg/mL (3.03mM),Need ultrasonic
DMSO:8 mg/mL (16.15 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years