Theobromine 是在可可豆中发现的一种甲基黄嘌呤,抑制腺苷受体 A1 信号传导,用作支气管扩张剂和血管扩张剂。
产品描述
3, 7-Dimethylxanthine, a xanthine alkaloid, is used as a bronchodilator and as a vasodilator.
体外活性
Theobromine (3,7-Dimethylxanthine) is a xanthine alkaloid that is used as a bronchodilator and as a vasodilator. [1] It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle. [2] Unlike caffeine, Theobromine has practically no stimulant effect on the central nervous system. In contrast, It may improve mood and cognition via peripheral physiological changes. [3] It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. [4]
体内活性
LD50: Rabbits >200 mg/kg (i.g.) [5]
Cas No.
83-67-0
分子式
C7H8N4O2
分子量
180.167
别名
3, 7-Dimethylxanthine;3,7-Dimethylxanthine;可可碱
储存和溶解度
DMSO:6 mg/mL (33.30 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years