CAS NO: | 1393330-40-9 |
包装 | 价格(元) |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Cas No. | 1393330-40-9 |
别名 | 丙炔基-四聚乙二醇-丙烯酸琥珀酰亚胺酯 |
分子式 | C18H27NO9 |
分子量 | 401.41 |
溶解度 | DMSO : 100 mg/mL (249.12 mM; Need ultrasonic) |
储存条件 | -20°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Propargyl-PEG5-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG5-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. [1]. Zhenjun Diwu, et al. Polyfluoreno[4,5-cde]oxepine Conjugates and Their Use in Methods of Analyte Detection. US20170275418A1. |