SuO-Glu-Val-Cit-PAB-MMAE

立即咨询

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1895916-24-1

包装与价格：

包装	价格(元)
1mg	电议
5mg	电议

产品介绍

SuO-Glu-Val-Cit-PAB-MMAE 由可降解 (cleavable) 的 ADC linker (SuO-Glu-Val-Cit-PAB) 和 MMAE 组成，MMAE 是一种有效的微管 (tubulin) 抑制剂。SuO-Glu-Val-Cit-PAB-MMAE可用于合成抗体偶联药物 (ADC)。

Cas No.	1895916-24-1
分子式	C67H103N11O17
分子量	1334.6
储存条件	-20°C, sealed storage, away from moisture and light,unstable in solution, ready to use.
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.