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hFSH-β-(33-53)(TFA)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
hFSH-β-(33-53)(TFA)图片
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
hFSH-β-(33-53) TFA 是一种含有硫醇的肽，对应于第二个FSH受体结合域，是 FSHR (卵泡刺激素受体) 拮抗剂。hFSH-β-(33-53) TFA 抑制FSH与受体的结合，是 Sertoli 细胞中雌二醇合成的部分激动剂。
分子式C117H184F3N31O34S
分子量2657.96
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

hFSH-β-(33-53) TFA, a thiol-containing peptide which corresponds to a second FSH receptor-binding domain, is a FSHR (follicle-stimulating hormone receptor) antagonist. hFSH-β-(33-53) TFA inhibits binding of FSH to receptor and is a partial agonist of estradiol synthesis in Sertoli cells[1][2][3].

[1]. Grasso P, et al. A synthetic peptide corresponding to hFSH-beta-(81-95) has thioredoxin-like activity. Mol Cell Endocrinol. 1991;78(3):163-170. [2]. Xu Y, et al. Pilot study of a novel (18)F-labeled FSHR probe for tumor imaging. Mol Imaging Biol. 2014;16(4):578-585. [3]. Santa-Coloma TA, et al. Serine analogues of hFSH-beta-(33-53) and hFSH-beta-(81-95) inhibit hFSH binding to receptor. Biochem Biophys Res Commun. 1992;184(3):1273-1279.