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(2-pyridyldithio)-PEG1-hydrazine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(2-pyridyldithio)-PEG1-hydrazine图片
CAS NO:111625-28-6
包装与价格:
包装价格(元)
50mg电议
100mg电议

产品介绍
(2-pyridyldithio)-PEG1-hydrazine 是一种可降解 (cleavable) 的含 1 个单元 PEG 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
Cas No.111625-28-6
别名2-[2-(吡啶基)连硫基]乙醇
分子式C7H9NOS2
分子量187.28
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.