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AM-Imidazole-PA-Boc
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AM-Imidazole-PA-Boc图片
CAS NO:2357108-99-5
包装:50mg
市场价:13950元

产品介绍
AM-Imidazole-PA-Boc 是一种 PROTAC linker,属于 alkyl chain 类。AM-Imidazole-PA-Boc 可用于合成 PROTAC IRAK4 degrader-1 。
Cas No.2357108-99-5
分子式C12H22N4O2
分子量254.33
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

AM-Imidazole-PA-Boc is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTAC IRAK4 degrader-1 [1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.