KN-92 hydrochloride 是 KN-93 的非活性衍生物,对 CaM 激酶无抑制作用。它可作为对照化合物用于阐明 KN-93 的拮抗活性。KN-93 是一种可渗透细胞的、可逆的、竞争性的 CaMKII 抑制剂。
产品描述
KN-92 hydrochloride is an inactive derivative of KN-93. KN-93 is a selective Ca2+/calmodulin-dependent kinase II (CaMKII) inhibitor, competitively blocking CaM binding to the kinase with Ki of 370 nM.
Cas No.
1431698-47-3
分子式
C24H26Cl2N2O3S
分子量
493.44
储存和溶解度
DMSO:40 mg/mL (81.06 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years