STO-609 acetate 是选择性的、细胞可渗透的 Ca2+-钙调蛋白依赖性蛋白激酶激酶抑制剂(Ki:80/15 ng/ml,对于 CaM-KKα/KKβ);竞争 ATP 结合位点。它比 CaMK1/2/4、PKC、MLCK、PKA 和 p42 MAPK 显示 >80 倍的选择性。
产品描述
STO-609 acetate is selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki: 80/15 ng/ml, for CaM-KKα/KKβ); competes for the ATP-binding site. It displays >80-fold selectivity over CaMK1/2/4, PKC, MLCK, PKA and p42 MAPK.
Cas No.
1173022-21-3
分子式
C19H10N2O3·C2H4O2
分子量
374.35
储存和溶解度
DMSO:10 mM,with sonication
Powder: -20°C for 3 years
In solvent: -80°C for 2 years