MethylnaLTRexone Bromide 是纳曲酮的四元衍生物，是可口服的外周作用 μ 阿片拮抗剂。它穿越血脑屏障的能力有限，可在胃肠道组织中发挥作用。

Methylnaltrexone, used in form of methylnaltrexone bromide, is one of the newer agents of peripherally-acting μ-opioid antagonists. Methylnaltrexone acts to reverse some of the side effects of opioid drugs such as constipation without affecting analgesia or precipitating withdrawals.

73232-52-7

C21H26BrNO4

436.35

MOA-728;Relistor;MOA728;Methylnaltrexone;MOA 728;溴化甲基纳曲酮

H2O:Insoluble
DMSO:60 mg/ml (137.5 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years