Uridine-5'-diphosphate disodium salt 是一种选择性P2Y6受体激动剂,EC50为300 nM,对人P2Y6受体的pEC50为6.52。它可刺激炎症介质的产生、吞噬作用和血管收缩,催化多种底物的葡糖醛酸糖化反应,用于核酸生物合成。
产品描述
UDP is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction. UDP also acts as an antagonist of P2Y14.
Cas No.
27821-45-0
分子式
C9H12N2Na2O12P2
分子量
448.12
别名
Uridine 5'-diphosphate disodium salt hyd;UDP disodium salt;尿苷-5'-二磷酸二钠盐
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years