CAS NO: | 1245823-51-1 |
包装 | 价格(元) |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
Cas No. | 1245823-51-1 |
别名 | 丙炔基-四聚乙二醇-乙酸 |
分子式 | C14H24O7 |
分子量 | 304.34 |
溶解度 | DMSO : 100 mg/mL (328.58 mM; Need ultrasonic) |
储存条件 | -20°C, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. [1]. Zhang H, et al. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors. Bioconjug Chem. 2018 Apr 18;29(4):1266-1275. |