| CAS NO: | 2183440-30-2 |
| 包装: | 5mg |
| 市场价: | 8820元 |
| Cas No. | 2183440-30-2 |
| 别名 | 生物素-PEG4-TCO |
| 分子式 | C29H50N4O8S |
| 分子量 | 614.79 |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | TCO-PEG4-biotin is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. [1]. Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. |
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