| CAS NO: | 104653-34-1 |
| 包装: | 1mg |
| 市场价: | 3850元 |
| Cas No. | 104653-34-1 |
| 别名 | 噻鼠灵 |
| Canonical SMILES | O=C1SC2=C(C(O)=C1C3C4=CC=CC=C4CC(C3)C5=CC=C(C6=CC=C(C=C6)Br)C=C5)C=CC=C2 |
| 分子式 | C31H23BrO2S |
| 分子量 | 539.5 |
| 溶解度 | Chloroform: slightly soluble,Methanol: slightly soluble |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Difethialone is an anticoagulant rodenticide and a vitamin K antagonist.1It binds to vitamin K epoxide reductase (VKOR; Kis = 0.04 and 0.05 µM for the wild-type and VKORY139Fenzyme, respectively). Difethialone is toxic to mice (LD50= 1.29 mg/kg).2Formulations containing difethialone have been used in the control of rodent pest populations. 1.Hodroge, A., Longin-Sauvageon, C., Fourel, I., et al.Biochemical characterization of spontaneous mutants of rat VKORC1 involved in the resistance to antivitamin K anticoagulantsArch. Biochem. Biophys.515(1-2)14-20(2011) 2.Vandenbroucke, V., Bousquet-Melou, A., De Backer, P., et al.Pharmacokinetics of eight anticoagulant rodenticides in mice after single oral administrationJ. Vet. Pharmacol. Ther.31(5)437-445(2008) |
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