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Ascorbyl Tetraisopalmitate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ascorbyl Tetraisopalmitate图片
CAS NO:183476-82-6
包装与价格:
包装价格(元)
5 g电议
10 g电议
25 g电议
50 g电议

产品介绍
A vitamin C derivative
Cas No.183476-82-6
别名四己基癸醇抗坏血酸酯
Canonical SMILESCCCCCCC(CCCCCCCC)C(OC[C@H](OC(C(CCCCCCCC)CCCCCC)=O)[C@@]1([H])OC(C(OC(C(CCCCCCCC)CCCCCC)=O)=C1OC(C(CCCCCC)CCCCCCCC)=O)=O)=O
分子式C70H128O10
分子量1129.8
溶解度DMF: 2 mg/ml,DMSO: insol,Ethanol: 10 mg/ml,PBS (pH 7.2): insol
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ascorbyl tetraisopalmitate is a lipophilic derivative of vitamin C .1,2It protects against UVB-, hydrogen peroxide-, ortert-butyl hydroperoxide-induced decreases in cell viability in HaCaT keratinocytes when used at a concentration of 100 µM.1Ascorbyl tetraisopalmitate (20 µM) decreases IL-1α and prostaglandin E2production in unstimulated and UVB-stimulated HaCaT keratinocytes. Topical application of ascorbyl tetraisopalmitate (1%) increases viable epidermis thickness, stratum corneum water content, and skin smoothness and decreases skin roughness in hairless mice.2Formulations containing ascorbyl tetraisopalmitate have been used in cosmetic products as skin-lightening agents.

1.Ochiai, Y., Kaburagi, S., Obayashi, K., et al.A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative propertiesJ. Dermatol. Sci.44(1)37-44(2006) 2.Maia Campos, P.M.B.G., Gianeti, M.D., Camargo, F.B., Jr., et al.Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: Stability studies and in vivo efficacyEur. J. Pharm. Biopharm.82(3)580-586(2012)