Acetylcholinesterase inhibitor
| Cas No. | 1953-04-4 |
| 别名 | 氢溴酸加兰他敏 |
| 化学名 | (4aS,6R,8aS)-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-benzo[2,3]benzofuro[4,3-cd]azepin-6-ol hydrobromide |
| Canonical SMILES | COC1=CC=C2C3=C1O[C@]4([H])[C@]3(C=C[C@H](O)C4)CCN(C)C2.Br |
| 分子式 | C17H21NO3.HBr |
| 分子量 | 368.27 |
| 溶解度 | ≥ 4.6 mg/mL in DMSO, ≥ 36.9 mg/mL in Water with ultrasonic and warming |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Long-acting, centrally active acetylcholinesterase inhibitor (IC50 = 410 nM) and allosteric potentiator at neuronal nicotinic ACh receptors. Prevents β-amyloid-induced apoptosis in SH-SY5Y and bovine chromaffin cells. Long-term administration reduces amyl |
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