Imipramine hydrochloride 可抑制血清素转运蛋白，IC50=32 nM。它可阻止胰酶的易位，阻碍 MV 和外泌体的分泌。

Imipramine (hydrochloride) is a first generation tricyclic antidepressant that acts primarily as an inhibitor of serotonin and norepinephrine transporters (Kds = 1.4 and 37 nM, respectively).Imipramine hydrochloride is reported to prevent the translocation of aSMase, inhibiting MV and exosomes secretion

113-52-0

C19H25ClN2

316.87

Melipramine;Imipramine HCl;Imipramine (hydrochloride);Tofranil;盐酸丙咪嗪;G 22355

DMSO:100 mg/mL (315.59 mM)
H2O:100 mg/mL (315.59 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years