Obtusin 是来自决明子种子，是一种高度选择性和竞争性的人单胺氧化酶-A抑制剂，IC50=11.12 μM，Ki=6.15 μM。它在神经退行性疾病，尤其是焦虑和抑郁中起预防作用。

Obtusin is a natural product.

Nine anthraquinones, aurantio-Obtusin (1), chryso-Obtusin (2), Obtusin (3), chryso-Obtusin-2-O-beta-D-glucoside (4), physcion (5), emodin (6), chrysophanol (7), obtusifolin (8), and obtusifolin-2-O-beta-D-glucoside (9), isolated from an EtOAc-soluble extract of the seeds of Cassia tora, were subjected to in vitro bioassays to evaluate their inhibitory activity against advanced glycation end products (AGEs) formation and rat lens aldose reductase (RLAR).

70588-05-5

C18H16O7

344.32

决明素;1,7-二羟基-2,3,8-三甲氧基-6-甲基蒽-9,10-二酮

DMSO:3.44 mg/mL(10 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years