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DBCO-PEG4-VA-PBD
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DBCO-PEG4-VA-PBD图片
CAS NO:2241644-09-5
包装:1mg
市场价:14850元

产品介绍
DBCO-PEG4-VA-PBD 是一种抗体偶联药物,由抗肿瘤抗生素 Pyrrolobenzodiazepine (PBD) 和 DBCO-PEG4-VA 连接而成。
Cas No.2241644-09-5
分子式C80H87N9O16
分子量1430.6
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DBCO-PEG4-VA-PBD is a drug-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via DBCO-PEG4-VA[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.