HS 024 是一种选择性的MC4受体拮抗剂，可增加食物摄入，对 MC4、MC5、MC3 和 MC1 的Ki分别为 0.29、3.29、5.45 和 18.6 nM。

Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.

212370-59-7

C58H79N19O10S2

1266.51

HS 024

H2O:0.50 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years