| CAS NO: | 170787-99-2 |
| 包装: | 50mg |
| 市场价: | 494元 |
| Cas No. | 170787-99-2 |
| 别名 | 乙丙昔罗钠,RSR13 sodium |
| 化学名 | sodium;2-[4-[2-(3,5-dimethylanilino)-2-oxoethyl]phenoxy]-2-methylpropanoate |
| Canonical SMILES | CC1=CC(=CC(=C1)NC(=O)CC2=CC=C(C=C2)OC(C)(C)C(=O)[O-])C.[Na+] |
| 分子式 | C20H23NO4.Na |
| 分子量 | 363.38 |
| 溶解度 | ≥ 18.4 mg/mL in DMSO, ≥ 12.83 mg/mL in Water with ultrasonic, ≥ 18.45 mg/mL in EtOH |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Efaproxiral sodium is a synthetic allosteric modifier of haemoglobin (Hb), decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy.in vitro: Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity. Increasing tumor oxygenation reduces tumor radioresistance. Efaproxiral can enhance the oxygenation of hypoxic tumours and function as a radiation sensitiser, increasing the effectiveness of RT. References: |
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