L-689560 是N-甲基-D-天冬氨酸受体（NMDA）的有效拮抗剂，抑制NMDA甘氨酸结合位点。它用于研究 NMDA 受体在正常神经系统过程以及疾病中的作用，也广泛用作结合研究中的放射性标记配体，也。

L-689560 is widely used as a radiolabeled ligand in binding studies and used to study the roles of NMDA receptors in normal neurological processes as well as in diseases. At the GluN1 glycine binding site, L-689560 is an effective N-methyl-D-aspartate (NMDA) receptor antagonist.

L-689560 is an antagonist of 2-carboxytetrahydroquinoline [2].

L-689560 blocks the glycine-induced increase of Akt phosphorylation in the MCAO model. L-689560 (1?mg/kg, ip) obviously decreases the neuroprotective effect of glycine after glycine receptors, and the channel activity of NMDA receptors (NMDARs) are suppressed [1].

139051-78-8

C17H15Cl2N3O3

380.23

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years