PralIDOxime chloride 是一种肟类化合物,对中毒乙酰胆碱酯酶具有恢复作用,可用于有机磷中毒的研究。
产品描述
Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, used to combat poisoning by acetylcholinesterase or organophosphates inhibitors (nerve agents) in combination with diazepam and atropine. Pralidoxime chloride has used in the therapy of organophosphate poisoning.
体外活性
The application of pralidoxime allowed the regeneration of an important fraction of inhibited AChE, process which is concentration-dependent[1].
Cas No.
51-15-0
分子式
C7H9ClN2O
分子量
172.61
别名
吡啶醛肟甲氯;2-PAM (chloride);2-Pyridinealdoxime methochloride;2-PAM chloride
储存和溶解度
DMSO:11.33 mg/mL (65.64 mM),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years