Nemorexant 是一种orexin受体拮抗剂，详细信息请参考专利文献 WO2015083094A1 中的化合物 example 7。它作用于Ox1和Ox2受体，IC50分别为 2 和 3 nM。

Daridorexant is an effective orexin receptor antagonist. It also has IC50s of 2 nM and 3 nM for the Ox1 receptor and Ox2 receptor, respectively.

Daridorexant is a orexin receptor antagonist with IC50s of 2 nM and 3 nM for Ox1 receptor and Ox2 receptor, respectively[1].

1505484-82-1

C23H23ClN6O2

450.92

Daridorexant;ACT-541468

DMSO:250 mg/mL (554.42 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years