Enbezotinib 是一种 RET 的抑制剂，可抑制 RET 的自磷酸化。Enbezotinib 可用于癌症的研究。

Enbezotinib, an inhibitor of RET, can inhibit the RET autophosphorylation. Enbezotinib can be used for the research of cancer.

Enbezotinib (compound 5) (0.3-300 nM) inhibits p-RET (y905) in RET-driven cells[1].

Enbezotinib (compound 5) (2-5 mg/kg; twice daily for 27 days) decreases tumor size in mice[1].

2359649-81-1

C21H21FN6O3

424.43

DMSO:90mg/mL (212mM),ultrasonic and warming and heat to 80°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years