RIPA-56 是一种高效选择和代谢稳定的受体相互作用蛋白 1 抑制剂，可研究全身炎症反应综合征，IC50为 13 nM。

RIPA-56 is an inhibitor of RIP1

In the SIRS mice disease model, RIPA-56?efficiently reduced tumor necrosis factor alpha (TNFα)-induced mortality and multi-organ damage.?Compared to known RIP1 inhibitors, RIPA-56?is potent in both human and murine cells, is much more stable in vivo, and is efficacious in animal model?studies.

1956370-21-0

C13H19NO2

221.3

DMSO:100 mg/mL (451.88 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years