WEHI-345 是一种选择性RIPK2 激酶抑制剂,IC50值为 0.13 μM。它在寡聚化结构域刺激下可延迟RIPK2的泛素化和NF-Κb的活化。
产品描述
WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.
Cas No.
1354825-58-3
分子式
C22H23N7O
分子量
401.474
别名
WEHI345
储存和溶解度
DMSO:32 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years