UTL-5g 是一种抗炎性TNF-α抑制剂，可通过抑制 TNF-α 等因子降低顺铂引起的肝毒性、肾毒性和骨髓毒性，具有化学保护和肝脏放射保护作用。

UTL-5g is a novel potential chemoprotective agent, TNF-α inhibitor that reduces cisplatin-induced side effects including nephrotoxicity, hepatotoxicity and hematotoxicity. It lowers elevated levels of AST, ALT, creatinine, BUN, and TNF-α, increases the reduced platelet count in mice, and acts as a novel chemo- and radioprotective agent.

UTL-5g (GBL-5g) lowers levels of TGF-β and TNF-α elevated by lung irradiation[1].

646530-37-2

C11H8Cl2N2O2

271.1

3-Isoxazolecarboxamide, N-(2,4-dichlorophenyl)-5-methyl-;GBL-5g

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years