4-Vinylphenol 是酒中乳酸菌对香豆酸和阿魏酸的代谢产物，在白花蛇舌草中发现。 4-Vinylphenol 在体内诱导细胞凋亡。

4-Vinylphenol is the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine found in Hedyotis diffusa Willd. 4-Vinylphenol induces apoptosis in vivo.

4-Vinylphenol (100 μg/mL) significantly increases the expressions of caspase 3, likely sensitizing CSC-enriched MDAMB-231 cells to apoptosis. 4-Vinylphenol (50, 100 μg/mL) significantly suppresses cell proliferation in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol (12.5-200 μg/mL) significantly reduces cell viability in parental MDA-MB-231 cells, and the IC50 value is 109 μg/mL. 4-Vinylphenol (0.15, 0.3 μg/mL) reduces sphere-formation and vimentin expression on CSCs in breast cancer. 4-Vinylphenol significantly reduces ALDH1A1 expression by 50% in CSC-enriched MDA-MB-231 cells[1].

2628-17-3

C8H8O

120.15

DMSO:145 mg/mL (1206.82 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years