IHR-1 是一种Smo拮抗剂,不能透过细胞膜。
产品描述
IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.
Cas No.
548779-60-8
分子式
C20H12Cl4N2O2
分子量
454.13
别名
IHR 1
储存和溶解度
DMSO:9.08 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years