CHIR 98024是一种有效的 GSK-3α/β 抑制剂,在无细胞试验中 IC50 为 0.65 nM/0.58 nM,能够区分 GSK-3 与其最接近的同源物 Cdc2 和 ERK2。
产品描述
CHIR 98024 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
Cas No.
556813-39-9
分子式
C20H17Cl2N9O2
分子量
486.31
别名
CHIR98014
储存和溶解度
H2O:<1 mgml
DMSO:8 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years