Netarsudil hydrochloride 是 Rho 相关蛋白激酶 (ROCK) 和去甲肾上腺素转运蛋白 (NET) 的抑制剂，可有效降低眼压 (IOP)。

Netarsudil Dihydrochloride is an inhibitor of Rho-associated protein kinase (ROCK) and norepinephrine transporter (NET) with effective in intraocular pressure (IOP) reduction.

Netarsudil Dihydrochloride (AR-13324 Dihydrochloride; 0.04%, 50 ΜL)reduces intraocular pressure (IOP) in normotensive monkey eyes [1]. Netarsudil Dihydrochloride (0.04%) produces a statistically significant lowering of episcleral venous pressure (EVP) in Dutch Belted rabbits [2].

1253952-02-1

C28H29Cl2N3O3

526.45

AR-13324 Dihydrochloride

DMSO:5 mg/mL (9.50 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years