Evodiamine 是一种生物碱，从萱草的果实中分离得到，具有多种生物活性，包括抗炎，抗肥胖和抗肿瘤。

Evodiamine, an indole alkaloid found in Evodia rutaescarpa, acts as an anti-inflammatory compound.

在小鼠中,静脉注射Evodiaminede的LD50为77 mg/kg.

在Bcl-2-和 Akt-过表达的U937细胞中,Evodiamine通过胱天蛋白酶非依赖性细胞凋亡途径,诱导细胞凋亡。

Evodiamine is dissolved in DMSO and diluted with appropriate medium before use. The evodiamine-inspired new scaffolds are assayed for growth inhibitory activities toward human cancer cell-lines A549 (lung cancer), MDA-MB-435 (breast cancer) and HCT116 (colon cancer) using the MTT assay. Evodiamine and camptithecin are used as reference drugs[1].

518-17-2

C19H17N3O

303.365

吴茱萸碱;d-Evodiamine;(+)-Evodiamine;Isoevodiamine

DMSO:39.6 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years