Dazoxiben 是口服具有活性的血栓烷合酶抑制剂。

Dazoxiben is a potent inhibitor of thromboxane (TX) synthase

Dazoxiben, an orally active TX-synthase inhibitor, on platelet and renal TXB2 production and associated changes in PG-endoperoxide metabolism. Dazoxiben inhibits TXB2 production in clotting human whole blood with an IC50 of 0.3 micrograms/ml and causes parallel enhancement of PGE2 greater than PGF2 alpha greater than 6-keto-PGF1 alpha production[1].

74226-22-5

C12H13ClN2O3

268.7

达唑氧苯;UK-37248

DMSO:62.5 mg/mL (232.60 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years