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surface antigen(208-215)[Hepatitis B Virus]
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
surface antigen(208-215)[Hepatitis B Virus]图片
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议

产品介绍

Surface antigen used for signs of infection

别名H2N-Ile-Leu-Ser-Pro-Phe-Leu-Pro-Leu-OH
Canonical SMILESNC(C(C)CC)C(NC(C(NC(CO)C(N1CCCC1C(NC(CC2=CC=CC=C2)C(NC(CC(C)C)C(N3CCCC3C(NC(C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)CC(C)C)=O
分子式C46H74N8O10
分子量899.13
溶解度≥ 89.9mg/mL in DMSO
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

The nucleocapsid of hepatitis B virus is covered by an envelope of HBV surface antigen (HBsAg), which has the common, group-specific determinant a. The four major subtypes of HBsAg, adw, adr, ayw and ayr, are generated, and they have been proposed to represent the phenotypic expression of the four major genotypes of HBV1. HBsAg subtypes show distinct geographical distributions2and may provide historical information on the migration of ancestors carrying HBV of a particular subtype3.

The HBsAg, localized on the surface of the infectious Dane particle is considered to be the antigen responsible for conferring immunity to infection with hepatitis B4. A larger amount is found on filaments of 20-nm diameter and variable length. By far the most HBsAg is present on small, noninfectious, 20-nm particles5.

Refences:
1.Le Bouvier, G. L., Mccollum, R. W., Hierholzer, W. J., Irwin, G. R., Krugman, S. & Giles, J. P. (1972). Subtypes of Australia antigen and hepatitis-B virus. Journal of the American Medical Association222, 928-930
2.Courouce-Pauty, A. M., Plancon, A. & Soulier, J. P. (1983). Distribution of HBsAg subtypes in the world. Vox sanguinis44, 197-211.
3.Yamashita, Y., Kurashina, S., Miyakawa, Y. & Mayumi, M. (1975). South-to-north gradient in distribution of the r determinant of hepatitis B surface antigen in Japan. Journal of Infectious Diseases131, 567-569.
4.A. M. Moriarty, B. H. Hoyeret al.Expression of the hepatitis B virus surface antigen gene in cell culture by using a simian virus 40 vector.Proc. Nati. Acad. Sci. 78: 2606-2610(1981).