7,4'-Dihydroxyflavone是从甘草中分离的类黄酮，是eotaxin/CCL11抑制剂，抑制嗜酸性粒细胞趋化因子产生。它通过调节 NF-Κb、STAT6 和 HDAC2，抑制MUC5A基因表达和粘液产生。

4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2.

Root exudate from 3-day-old alfalfa seedlings was purified and then assayed for biological activity with a nodABC-lacZ fusion in R. meliloti. Indentities of major nod inducers were established by spectroscopic analyses (ultraviolet/visible, proton nuclear magnetic resonance, and mass spectroscopy) and comparison with authentic standards. Major nod inducers, which were identified as 4',7-Dihydroxyflavone, 4'-7-dihydroxyflavanone, and 4,4'-dihydroxy-2'-methoxychalcone, were released from seedling roots at 54, 22, and 20 picomole.plant(-1).day(-1), respectively. Luteolin was not found in these root exudates.

2196-14-7

C15H10O4

254.24

7,4'-二羟基黄酮;4',7-Dihydroxyflavone

DMSO:250 mg/mL (983.32 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years