Nimodipine 是一种具有口服活性,耐受性良好的光敏二氢吡啶钙拮抗剂。它可研究脑血管疾病。
产品描述
Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.
体内活性
Nimodipine (5-20 mg/kg, SC) suppresses in a dose-related manner self-administration both of cocaine and morphine contingent upon a nose-poke response. Nimodipine (10 mg/kg, SC), an L-type dihydropyridine Ca2+ channel antagonist, exhibits to completely block the establishment of conditioning of cocaine's effects, but only partially blocks sensitization to cocaine.
Cas No.
66085-59-4
分子式
C21H26N2O7
分子量
418.44
别名
BAY-e 9736;尼莫地平
储存和溶解度
DMSO:41.8 mg/mL (100 mM)
Ethanol:4.2 mg/mL (10 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years