GLX351322 抑制 NADPH 氧化酶 4 (Nox4) 。在 NOX4 过表达的细胞中,抑制过氧化氢的产生,IC50值为 5 μM。
产品描述
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
体外活性
In long-term experiments (1-3 days), high-glucose-induced human islet cell reactive oxygen species (ROS) production and death were prevented by GLX351322.
Cas No.
835598-94-2
分子式
C21H25N3O5S
分子量
431.51
储存和溶解度
DMSO:20 mg/mL (46.35 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years