Etalocib 是一种具有口服活性的白三烯(LTB4)受体的拮抗剂，抑制 [3H]LTB4结合的Ki值为 25 nM。它还可诱导凋亡。它抑制LTB4诱导的钙动员，lC50值为 20 nM。

Etalocib is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotriene B4 (LTB4) receptor or directly through 5'-lipoxygenase. It has antineoplastic activities.

161172-51-6

C33H33FO6

544.61

LY293111;VML295

DMSO:100 mg/mL (183.62 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years