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Trandolapril
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Trandolapril图片
CAS NO:87679-37-6
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
50mg电议
100mg电议

产品介绍
群多普利 (RU44570) 是一种非巯基前药，可水解为活性二酸群多普利拉。
Cas No.87679-37-6
别名群多普利; RU44570
化学名(2S,3aR,7aS)-1-((S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)octahydro-1H-indole-2-carboxylic acid
Canonical SMILESO=C([C@@H](N[C@H](C(OCC)=O)CCC1=CC=CC=C1)C)N2[C@H](C(O)=O)C[C@@]3([H])CCCC[C@@]32[H]
分子式C24H34N2O5
分子量430.54
溶解度DMF: 15 mg/ml,DMSO: 25 mg/ml,Ethanol: 0.25 mg/ml,PBS (pH 7.2): 1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Trandolapril (RU44570) is a nonsulfhydryl prodrug that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI)[1].

References:
[1]. Peters DC, et al. Trandolapril. An update of its pharmacology and therapeutic use in cardiovascular disorders. Drugs. 1998 Nov;56(5):871-93.